| 1. | We did not find the c57 1t c628t . . c658t or a375g point mutations in both populations
在两个人群中均未检测到携带c571t 、 c628t 、 c658t和a375g点突变的个体。 |
| 2. | Mms , a kind of dna - damaging agent , predominantly methylates ring nitrogens of pyrine , leading to dna double - strand breaks , point mutation and so on
甲磺酸甲酯( methylmetbanesulfonate ， mms )是一种能够损伤dna的烷化剂，主要使dna嘌呤碱基上的o 、 n甲基化，造成dna双链断裂、点突变。 |
| 3. | The point mutation in vp2 residue 297 of canine parvovirus from ser to ala acid was examined , which causes a alteration of the restriction enzyme aiu i site
根据vp2位点297的改变引起限制性内切酶aiu酶切位点的变化，建立pcr依赖性限制性片段长度多态性分析( prfl )方法，检测vp2位点297的变异。 |
| 4. | To establish a simple , inexpensive , rapid technology to detect point mutation or snp of mbl gene with high sensitivity and specificity , which should be of utility in the most of medical laboratories in our country
建立敏感性高、特异性强、简单快捷、适合我国国情(条件较差)的mbl基因点突变和snp的检测技术。 |
| 5. | The analysis was conducted using special mice that hae been genetically manipulated to more easily detect point mutations . dna was extracted from fetuses at mid - gestation , about 10 days past conception
检测分析是通过在一种经过基因处理后较容易检测点突变的特殊老鼠身上进行。 dna从受孕大约10天后的中期妊娠胚胎中提取。 |
| 6. | On the contrary , biology has catalogued many traits produced by point mutations ( changes at precise positions in an organism ' s dna ) ? bacterial resistance to antibiotics , for example
实情恰恰相反。在生物的dna上，某个特定位址发生的变化叫作点突变。生物学家已经发现许多点突变制造的性状，例如细菌对抗生素的耐受本领。 |
| 7. | Results : ( 1 ) sequencing of katg from 101 inh - resistant strains showed point mutations , small deletions or insertions in 81 isolates ( 80 . 20 % ) , but no complete deletions were identified
结果( 1 ) 101株耐异烟肼结核分枝杆菌临床分离株中未发现katg基因完全缺失。共检测到80 . 20 ( 81 / 101 )的菌株存在点突变、小的缺失或插入。 |
| 8. | With strong specificity and easy to manipulation , this simple , inexpensive , rapid molecular beacon hybridization technique permits visual monitoring of gene point mutation and snp , which shows better advantage than pcr - sscp . 2
Mb杂交技术特异性强，简单快捷，能进行可视性检测，完全适用于点突变和snp的研究，技术特点明显优于pcr sscp 。 |
| 9. | In addition , the results of dna direct sequencing reveal that 1 out of 18 rifampin - resistant isolates has deletion in codons 513 and 514 of rpob , and the other 17 are all singe - point mutation in their rpob genes
此外， dna直接测序结果显示， 18株耐利福平菌株中，一株rpob基因的513 、 514位密码子发生了缺失，其它17株的rpob基因皆发生了单碱基突变。 |
| 10. | The normal allele is known as a . each variant is the result of a single point mutation in exon 1 that disrupts the collagen - like structure of the mbl polypeptide . this leads to a reduction of functional mbl in individuals
每一种变异体均由单碱基突变引起，致使mbl分子的胶原样区发生改变，导致突变个体血清mbl水平低下，有可能突变mbl分子的功能也受损。 |
